Tushar Deshpande, a specialist right-arm medium-fast bowler and left-handed batter, was born on May 15, 1995, in Mumbai. Emerging onto the Mumbai cricketing circuit, Deshpande made a significant impact during the 2015-16 season of the Cooch Behar Trophy, claiming 21 wickets in just four matches.

His standout performances led to his selection in the Mumbai Ranji Trophy team the same year, making his debut against Tamil Nadu on September 19. In the Vijay Hazare Trophy held on September 19, 2018, he made his List A debut for Mumbai against Baroda at Alur, where he showcased his talent by securing a five-wicket haul during the competition's quarter-final.

Deshpande's consistency in white-ball cricket earned him a spot in the India 'B' side for the Duleep Trophy in August 2019. This further highlighted his potential as a promising fast bowler in the domestic circuit, drawing attention from the teams of the INDIAN T20 LEAGUE. In the INDIAN T20 LEAGUE auction for the 2020 season, Deshpande was picked up by Delhi at his base price. Despite playing six games for the franchise and securing three wickets, it wasn't a standout season for the young cricketer.

In the mega auction for INDIAN T20 LEAGUE 2022, Tushar Deshpande's talent didn't go unnoticed as he was acquired by the Chennai team at his base price of INR 20 Lakhs. Since then, he has been part of the team in yellow and even went on to win the title with them in the 2023 season.